Prevalence of Hepatitis B Infection in Iranian Pregnant Women: A Systematic Review and Meta-analysis

Abstract

Background:

One of the most sensitive periods of a person's life, which has a great impact on his future health, is the fetal period, while the risk of infection in children of mothers who are positive in terms of HBsAg serum level is very high. Therefore, the aim of this systematic review and meta-analysis is to determine the prevalence of hepatitis B infection in Iranian pregnant women.

Materials and Methods:

This study is a systematic review and meta-analysis by examining Scientific Information Database (SID), Medline (PubMed), ScienceDirect and Google Scholar until February 2024.

Results:

In a review of 45 studies with a sample size of 77,641 pregnant women, based on meta-analysis, the prevalence of hepatitis B infection in Iranian pregnant women was reported to be 1.1% (95% CI: 0.9-1.4 %), meta-regression results showed that with increasing The sample size, the prevalence of hepatitis B infection in Iranian pregnant women decreased (P<0.05) and also with the increase in the years of conducting studies, the prevalence of hepatitis B infection in Iranian pregnant women decreased (P<0.05) and also with the increasing age of women. pregnant, the prevalence of hepatitis B infection increases in Iranian pregnant women (P=0.133).

Conclusion:

The results of the present study show that the prevalence of hepatitis B infection in Iranian pregnant women is not at a high level, but according to the meta-regression analysis, which shows the effect of age at the same time as the increase of this infection in women, it is necessary to continue preventive measures and reach The lower levels of attention of health policy makers in this area should be directed to carry out extensive information and screening.