Portal Vein Phasic Flow in Patients with Severe Fatty Liver without Cirrhotic Changes

Abstract

Background:

Non-alcoholic fatty liver disease is the most common cause of liver diseases in many developed countries, leading to chronic liver disease.

Objectives: This study aimed to investigate the phasic flow of the portal vein in patients with severe fatty liver without cirrhotic changes.

Materials and Methods:

This cross-sectional study included 40 patients aged 18 years or older who were referred to Taleghani Hospital over the past year and underwent ultrasonography. In these patients, portal vein phasic flow in severe fatty liver (Grades 2 and 3) without cirrhotic changes was measured and quantified by ultrasonography. After identifying the samples, data collection was completed by performing an ultrasound and blood tests according to the study objectives. Data were analyzed using SPSS software version 25, and the significance level was set at P < 0.05.

Results:

55% of the cases were men, and 45% were women. Most of the study samples (92.5%) reported no disease. The Maximum Velocity) Vmax (distribution is mainly concentrated between 13 and 22; the presence of a very large value of 120 indicates a potential outlier and a significant effect on the mean. Minimum Velocity) Vmin) is mostly in the range of 10 to 14, and a value of 90 indicates a potential outlier.

Conclusion:

 The present study showed no significant difference in frequency between the two sexes. The results also indicated that the maximum peak velocity, minimum peak velocity, mean flow velocity, portal vein pulsatility index, and hepatic artery resistance index were significantly lower in non-alcoholic fatty liver disease.