Uncommon Presentation of Gastric Adenocarcinoma: Report of Two Cases

Abstract

Adenocarcinoma of the stomach was the leading cause of cancer-related death worldwide through most of the 20th century. Usual presentations of gastric cancer include anorexia, epigastric pain or discomfort and weakness. Rarely, patients present with unusual clinical manifestations. In this article, we report two cases with uncommon presentations of gastric adenocarcinoma. The first patient was a 52-year-old male presented with testicular mass, and the second case was a 51- year-old female presenting with diffuse bone pain, petechiae and purpura on the skin of abdomen. In the first case, the initial pathologic specimen was provided from testicular mass (orchiectomy) and for the second case, bone marrow biopsy was done. The initial reports for these cases were seminoma and metastatic signet ring carcinoma, respectively. Chemotherapy was done for both.Gastric adenocarcinoma rarely presents with unusual clinical manifestations. Chemotherapy in one out of two cases showed good palliative results.