Wegner’s Granulomatosis with Gastrointestinal Manifestation: a Case Report

Abstract

A 55 year-old man was referred with periumbilical and colicky abdominal painØŒ cutaneous lesionsØŒ palpable purpura in extremities and 10 kg weight loss. A 5×5 cm cavitary mass lesion was seen in the lower lobe of right lung in CXR. Pansinusitis in paranasal CT scan was reported. Intramural hemorrhage in ileum and jejunum in abdominal CT scan was noted. ESR was ›100 and C-ANCAwas positive.Microscopic hematuria was reported in lab studies.Wegner's granulomatosis was diagnosed and prednisolone plus cyclophosphamide was administered. He was improved dramatically in a few days.After 3 monthsØŒ he had no symptoms or signs, lab data were normal and lung mass lesion became smaller.After six monthsØŒ he had deep vein thrombosis in left lower extremity.