A Case Report of Pegylated Interferon and Bronchiolitis Oblitrans with Organizing Pneumonia

Ahmad Khosravi, Mohammad Towhidi, Hassan Vosoughinia, Kamran Ghaffarzadehgan, Shahrzad M.Lari, Tahmineh Tavakkoli


A 46-year-old woman presented with progressive dyspnea and cough. She was a known case of chronic hepatitis C (HCV) treated with pegylated (PEG)-interferon. Complete pulmonary studies and biopsy were compatible with bronchiolitis oblitrans with organizing pneumonia (BOOP) secondary to PEG-interferon. She discontinued PEG-interferon and was given a short course of steroids, after which the condition completely resolved. This report has shown that particular attention to possible side effects of PEG-interferon is necessary in the clinical practice.


Bronchiolitis oblitrans with organizing pneumonia (BOOP); pegylated (PEG)-interferon; Hepatitis C virus (HCV); Iran.

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